NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
National Institutes of Health · Department of Health and Human Services · PA-25-306
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Jan 7, 2028 (422 days left).
The listing does not state award amounts or the number of awards.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Jan 7, 2028 · 422 days left |
| Posted date | Dec 18, 2024 |
| Opportunity number | PA-25-306 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Grant |
| Category | Education, Environment, Health, Income Security and Social Services |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | Not stated |
| Expected number of awards | Not stated |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.113 – Environmental Health 93.143 – NIEHS Superfund Hazardous Substances_Basic Research and Education 93.172 – Human Genome Research 93.173 – Research Related to Deafness and Communication Disorders 93.213 – Research and Training in Complementary and Integrative Health 93.233 – National Center on Sleep Disorders Research 93.242 – Mental Health Research Grants 93.273 – Alcohol Research Programs 93.279 – Drug Use and Addiction Research Programs 93.286 – Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 – Minority Health and Health Disparities Research 93.361 – Nursing Research |
| Last updated on Grants.gov | Sep 4, 2025 |
| Archive date | Feb 12, 2028 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. …
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. …
Read the full listing on Grants.gov → · Agency's announcement page
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