HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services · RFA-AT-25-003
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Nov 23, 2026 (12 days left).
Awards are up to $375,000 each.
Eligible applicant types include colleges & universities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Nov 23, 2026 · 12 days left |
| Posted date | Jan 8, 2025 |
| Opportunity number | RFA-AT-25-003 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Grant |
| Category | Health, Income Security and Social Services |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | $375,000 |
| Award floor (min per award) | Not stated |
| Estimated total program funding | Not stated |
| Expected number of awards | Not stated |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.121 – Oral Diseases and Disorders Research 93.213 – Research and Training in Complementary and Integrative Health 93.273 – Alcohol Research Programs 93.846 – Arthritis, Musculoskeletal and Skin Diseases Research 93.853 – Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 – Child Health and Human Development Extramural Research 93.866 – Aging Research |
| Last updated on Grants.gov | Jan 8, 2025 |
| Archive date | Dec 29, 2026 |
Who can apply
Browse similar: Colleges & universities
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.
Read the full listing on Grants.gov → · Agency's announcement page
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