Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
National Institutes of Health · Department of Health and Human Services · PAR-27-012
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this cooperative agreement until Nov 2, 2028 (722 days left).
The listing does not state award amounts or the number of awards.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Nov 2, 2028 · 722 days left |
| Posted date | Mar 18, 2026 |
| Opportunity number | PAR-27-012 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Cooperative agreement |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | Not stated |
| Expected number of awards | Not stated |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.233 – National Center on Sleep Disorders Research 93.837 – Cardiovascular Diseases Research 93.838 – Lung Diseases Research 93.839 – Blood Diseases and Resources Research 93.840 – Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders |
| Last updated on Grants.gov | Mar 18, 2026 |
| Archive date | Jan 2, 2029 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. …
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct a Clinical Coordinating Center (CCC) for investigator-initiated multi-site clinical trials including efficacy, comparative effectiveness, pragmatic and/or dissemination and implementation science clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, dissemination and implementation science clinical trials and/or prevention strategies.Trials for which this NOFO applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial (see NOT-OD-15-015). …
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