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Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)

National Institutes of Health · Department of Health and Human Services · RFA-OD-25-010

In plain English

National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Sep 28, 2028 (687 days left).

The agency expects to make 6 awards and estimated total program funding is $5,000,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations and colleges & universities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusPosted: open for applications
Close dateSep 28, 2028 · 687 days left
Posted dateDec 5, 2025
Opportunity numberRFA-OD-25-010
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentGrant
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)Not stated
Award floor (min per award)Not stated
Estimated total program funding$5,000,000
Expected number of awards6
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.351 – Research Infrastructure Programs
Last updated on Grants.govDec 24, 2025
Archive dateNov 2, 2028

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities

  • State governments
  • County governments
  • City or township governments
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Refer to Section III. Eligibility Information of the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Description

Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):

The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs) applicable to human health and diseases; or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple organ systems in order to align with the ORIP"s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs. …

Read the full listing on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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