Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services · RFA-HL-27-004
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Nov 7, 2028 (727 days left).
Awards are up to $85,000 each, the agency expects to make 29 awards and estimated total program funding is $3,900,000.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Nov 7, 2028 · 727 days left |
| Posted date | May 12, 2026 |
| Opportunity number | RFA-HL-27-004 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Grant |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | $85,000 |
| Award floor (min per award) | Not stated |
| Estimated total program funding | $3,900,000 |
| Expected number of awards | 29 |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.233 – National Center on Sleep Disorders Research 93.837 – Cardiovascular Diseases Research 93.838 – Lung Diseases Research 93.839 – Blood Diseases and Resources Research 93.840 – Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders |
| Last updated on Grants.gov | Sep 3, 2026 |
| Archive date | Jan 6, 2029 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Only the following NHLBI K01, K08, K23, and K25 awardees are eligible to apply for this funding opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees. Current NHLBI K01, K08, K23, and K25 awardees may apply for this R03 support starting in the third year of their K award Project Period. …
More Department of Health and Human Services grants closing soon
All →- 2days leftNCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)NonprofitsSmall businessesFor-profit companies+6 moreHealth
- 2days leftNCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)NonprofitsSmall businessesFor-profit companies+6 moreHealth
- 2days leftNCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)NonprofitsSmall businessesFor-profit companies+6 moreHealth
- 2days leftNIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)NonprofitsSmall businessesFor-profit companies+6 moreEducation
More health grants closing soon
All →- 5days leftEthical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)NonprofitsSmall businessesFor-profit companies+6 moreEducation
- 6days leftSingle Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)NonprofitsSmall businessesFor-profit companies+6 moreHealth
- 6days leftPrevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)NonprofitsSmall businessesFor-profit companies+6 moreHealth
- 6days leftFeasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)NonprofitsSmall businessesFor-profit companies+6 moreHealth