Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services · PAR-26-121
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until May 26, 2028 (562 days left).
The listing does not state award amounts or the number of awards.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | May 26, 2028 · 562 days left |
| Posted date | Dec 11, 2025 |
| Opportunity number | PAR-26-121 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Grant |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | Not stated |
| Expected number of awards | Not stated |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.859 – Biomedical Research and Research Training |
| Last updated on Grants.gov | Dec 18, 2025 |
| Archive date | Jul 25, 2028 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. …
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The Maximizing Investigators' Research Award (MIRA) provides support for individual investigators for research within the scientific mission of NIGMS via a single grant to achieve the following:Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively;Increase flexibility for investigators to follow important new research directions within the NIGMS mission as opportunities arise, rather than being bound to specific aims proposed in advance of the studies;More widely distribute funding among the nation's highly talented and promising investigators to increase overall scientific productivity and the chances for important breakthroughs;Reduce the time spent by researchers writing and reviewing grant applications, allowing them to spend more time conducting …
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