Grant Deadlines
OpenCooperative agreement

BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services · RFA-NS-28-010

In plain English

National Institutes of Health (Department of Health and Human Services) is accepting applications for this cooperative agreement until Feb 8, 2029 (820 days left).

The agency expects to make 5 awards and estimated total program funding is $8,000,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusPosted: open for applications
Close dateFeb 8, 2029 · 820 days left
Posted dateSep 30, 2026
Opportunity numberRFA-NS-28-010
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentCooperative agreement
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)Not stated
Award floor (min per award)Not stated
Estimated total program funding$8,000,000
Expected number of awards5
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.173 – Research Related to Deafness and Communication Disorders
93.213 – Research and Training in Complementary and Integrative Health
93.242 – Mental Health Research Grants
93.273 – Alcohol Research Programs
93.279 – Drug Use and Addiction Research Programs
93.286 – Discovery and Applied Research for Technological Innovations to Improve Human Health
93.372 – 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies
93.853 – Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 – Child Health and Human Development Extramural Research
93.866 – Aging Research
93.867 – Vision Research
Last updated on Grants.govSep 30, 2026
Archive dateApr 10, 2029

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. …

Description

Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):

This funding opportunity supports transformative, mechanistic research aimed at understanding how the human brain functions. Applications should seek to reveal how the dynamic activity of individual neurons and ensembles of neurons within spatially organized brain networks gives rise to internal experiences, such as sensations, perceptions, emotions, thoughts, and memories, as well as to observable motor and social behaviors. To achieve fundamental mechanistic insights into human brain function, proposed studies are expected to leverage opportunities made possible by invasive surgical procedures in humans, such as intracranial recording or stimulation. These investigations may be enhanced by incorporating complementary experimental models or systems that provide access to knowledge, techniques, or resources not otherwise available in human neuroscience research. …

Read the full listing on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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