Grant Deadlines
OpenGrantUp to $200K per award

INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services · RFA-OD-27-003

In plain English

National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Jun 15, 2028 (582 days left).

Awards are up to $200,000 each, the agency expects to make 5 awards and estimated total program funding is $1,000,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusPosted: open for applications
Close dateJun 15, 2028 · 582 days left
Posted dateMay 12, 2026
Opportunity numberRFA-OD-27-003
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentGrant
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)$200,000
Award floor (min per award)Not stated
Estimated total program funding$1,000,000
Expected number of awards5
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.121 – Oral Diseases and Disorders Research
93.173 – Research Related to Deafness and Communication Disorders
93.233 – National Center on Sleep Disorders Research
93.310 – Trans-NIH Research Support
93.351 – Research Infrastructure Programs
93.395 – Cancer Treatment Research
93.837 – Cardiovascular Diseases Research
93.838 – Lung Diseases Research
93.839 – Blood Diseases and Resources Research
93.840 – Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
93.846 – Arthritis, Musculoskeletal and Skin Diseases Research
93.855 – Allergy and Infectious Diseases Research
Last updated on Grants.govMay 12, 2026
Archive dateAug 14, 2028

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Description

Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. …

Read the full listing on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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