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Rigor and Reproducibility for Biomarkers in Type 1 Diabetes Clinical Research

National Institutes of Health · Department of Health and Human Services · RFA-DK-27-140

In plain English

National Institutes of Health (Department of Health and Human Services) has announced this as a forecast: an opportunity it expects to post. It is not open for applications yet. Estimated posting date: Apr 1, 2026 (this estimate has passed and the agency has not posted it yet). Estimated application due date: Jun 25, 2026.

The agency expects to make 8 awards and estimated total program funding is $5,200,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusForecasted: not open yet
Estimated posting dateApr 1, 2026 (estimate has passed)
Estimated application due dateJun 25, 2026
Estimated award dateApr 1, 2027
Estimated project startMay 1, 2027
Fiscal year2027
Forecast postedFeb 4, 2026
Opportunity numberRFA-DK-27-140
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentGrant
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)Not stated
Award floor (min per award)Not stated
Estimated total program funding$5,200,000
Expected number of awards8
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.847 – Diabetes, Digestive, and Kidney Diseases Extramural Research
Last updated on Grants.govFeb 4, 2026

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Description

Excerpt from the official forecast on Grants.gov (shortened; read the full text on the official listing):

The main goal of this initiative is to establish a consortium with the overarching goal to advance the systematic identification, rigorous evaluation, validation, and assays harmonization of biomarkers that are critical to the prevention, diagnosis, and clinical management of Type 1 Diabetes (T1D). Despite significant advances in T1D research, there remains an urgent need for reliable and reproducible biomarkers that can capture the complexity of autoimmune processes, metabolic dysregulation, and individual patient variability. This initiative will leverage state-of-the-art methodologies in clinical chemistry, genomics, proteomics, metabolomics, immunophenotyping, and imaging, coupled with longitudinal patient cohorts and mining of Electronic Health Records (EHR). …

Read the full forecast on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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