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NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services · RFA-EB-28-004

In plain English

National Institutes of Health (Department of Health and Human Services) is accepting applications for this grant until Dec 1, 2030 (1481 days left).

The agency expects to make 4 awards and estimated total program funding is $6,000,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusPosted: open for applications
Close dateDec 1, 2030 · 1481 days left
Posted dateOct 23, 2026
Opportunity numberRFA-EB-28-004
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentGrant
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)Not stated
Award floor (min per award)Not stated
Estimated total program funding$6,000,000
Expected number of awards4
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.121 – Oral Diseases and Disorders Research
93.242 – Mental Health Research Grants
93.273 – Alcohol Research Programs
93.279 – Drug Use and Addiction Research Programs
93.286 – Discovery and Applied Research for Technological Innovations to Improve Human Health
93.853 – Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 – Child Health and Human Development Extramural Research
93.866 – Aging Research
93.867 – Vision Research
Last updated on Grants.govOct 23, 2026
Archive dateFeb 1, 2031

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Description

Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):

This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

Read the full listing on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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