The Genesis Mission: Transforming Science and Energy with AI
Office of Science · Department of Energy - Office of Science · DE-FOA-0003612
In plain English
Office of Science (Department of Energy - Office of Science) is accepting applications for this other until Dec 17, 2026 (36 days left).
Individual awards range from $500,000 to $16,000,000 and estimated total program funding is $293,760,000.
Eligibility is listed as unrestricted (open to any type of applicant), subject to any clarification in the listing.
Cost sharing or matching is required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Dec 17, 2026 · 36 days left |
| Posted date | Mar 17, 2026 |
| Opportunity number | DE-FOA-0003612 |
| Agency | Office of Science (Department of Energy - Office of Science) |
| Funding instrument | Other |
| Category | Science and Technology and other Research and Development |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | $16,000,000 |
| Award floor (min per award) | $500,000 |
| Estimated total program funding | $293,760,000 |
| Expected number of awards | Not stated |
| Cost sharing or matching required | Yes |
| Assistance listing (CFDA/ALN) | 81.049 – Office of Science Financial Assistance Program |
| Last updated on Grants.gov | Apr 10, 2026 |
| Archive date | Mar 17, 2027 |
Who can apply
- Unrestricted (open to any type of entity above, subject to clarification in the listing)
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. …
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