Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services · PAR-27-040
In plain English
National Institutes of Health (Department of Health and Human Services) has announced this as a forecast: an opportunity it expects to post. It is not open for applications yet. Estimated posting date: Nov 5, 2026 (this estimate has passed and the agency has not posted it yet). Estimated application due date: Jan 5, 2027.
The listing does not state award amounts or the number of awards.
Eligible applicant types include small businesses.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Forecasted: not open yet |
|---|---|
| Estimated posting date | Nov 5, 2026 (estimate has passed) |
| Estimated application due date | Jan 5, 2027 |
| Estimated award date | Jun 1, 2027 |
| Estimated project start | Jul 1, 2027 |
| Fiscal year | 2027 |
| Forecast posted | May 27, 2026 |
| Opportunity number | PAR-27-040 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Grant |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | Not stated |
| Expected number of awards | Not stated |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.113 – Environmental Health 93.121 – Oral Diseases and Disorders Research 93.172 – Human Genome Research 93.173 – Research Related to Deafness and Communication Disorders 93.213 – Research and Training in Complementary and Integrative Health 93.233 – National Center on Sleep Disorders Research 93.273 – Alcohol Research Programs 93.279 – Drug Use and Addiction Research Programs 93.350 – National Center for Advancing Translational Sciences 93.361 – Nursing Research 93.837 – Cardiovascular Diseases Research 93.838 – Lung Diseases Research |
| Last updated on Grants.gov | May 27, 2026 |
Who can apply
Browse similar: Small businesses
- Small businesses
Additional eligibility information (excerpt from the listing):
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Description
Excerpt from the official forecast on Grants.gov (shortened; read the full text on the official listing):
The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant. Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. …
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