Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)
National Institutes of Health · Department of Health and Human Services · RFA-AI-28-014
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this cooperative agreement until Feb 18, 2027 (99 days left).
Awards are up to $2,500,000 each, the agency expects to make 10 awards and estimated total program funding is $26,000,000.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Feb 18, 2027 · 99 days left |
| Posted date | Nov 4, 2026 |
| Opportunity number | RFA-AI-28-014 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Cooperative agreement |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | $2,500,000 |
| Award floor (min per award) | Not stated |
| Estimated total program funding | $26,000,000 |
| Expected number of awards | 10 |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.121 – Oral Diseases and Disorders Research 93.172 – Human Genome Research 93.543 – Vision Research - Research Projects 93.8AM – National Institute of Allergy and Infectious Diseases-Antimicrobial Resistance 93.8RP – National Institute of Allergy and Infectious Diseases- Research Projects 93.8TD – National Institute of Allergy and Infectious Diseases-Tickborne Diseases 93.ADR – NIH Office for Research on Women's Health - Office of Autoimmune Research 93.AGR – National Institute on Aging Research Projects 93.AR1 – Arthritis, Musculoskeletal and Skin Diseases Research - Research Projects 93.DSS – NIH Office of Data Science Strategy (ODSS) 93.HL2 – National Heart, Lung, and Blood Institute - Research Projects |
| Last updated on Grants.gov | Nov 4, 2026 |
| Archive date | Apr 18, 2027 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The purpose of this notice of funding opportunity (NOFO) is to support the advancement of systems-level understanding of the link between infectious pathogens and inflammatory pathways that result in predisposition, onset and progression of chronic diseases. The NOFO will stimulate integration of clinical and patient data, large-scale omics datasets, advanced Artificial Intelligence (AI) and computational modeling to prevent, treat, and mitigate the combined impact of chronic diseases, inflammation, and infections.
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