Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
National Institutes of Health · Department of Health and Human Services · RFA-AI-28-012
In plain English
National Institutes of Health (Department of Health and Human Services) is accepting applications for this cooperative agreement until Jan 29, 2027 (79 days left).
The agency expects to make 5 awards and estimated total program funding is $7,000,000.
Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Posted: open for applications |
|---|---|
| Close date | Jan 29, 2027 · 79 days left |
| Posted date | Oct 20, 2026 |
| Opportunity number | RFA-AI-28-012 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Cooperative agreement |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | $7,000,000 |
| Expected number of awards | 5 |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.310 – Trans-NIH Research Support 93.855 – Allergy and Infectious Diseases Research |
| Last updated on Grants.gov | Oct 20, 2026 |
| Archive date | Mar 29, 2027 |
Who can apply
Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Description
Excerpt from the official synopsis on Grants.gov (shortened; read the full text on the official listing):
The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. …
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