Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)
National Institutes of Health · Department of Health and Human Services · RFA-DK-28-115
In plain English
National Institutes of Health (Department of Health and Human Services) has announced this as a forecast: an opportunity it expects to post. It is not open for applications yet. Estimated posting date: Feb 2, 2027. Estimated application due date: Mar 10, 2027.
The agency expects to make 1 award and estimated total program funding is $35,000,000.
Eligibility is described in the listing text (the "Others" category).
The listing says cost sharing or matching is not required.
Built only from the fields in the Grants.gov listing. Always confirm on the official listing.
Key facts
| Status | Forecasted: not open yet |
|---|---|
| Estimated posting date | Feb 2, 2027 |
| Estimated application due date | Mar 10, 2027 |
| Estimated award date | Nov 1, 2027 |
| Estimated project start | Dec 1, 2027 |
| Fiscal year | 2028 |
| Forecast posted | Aug 4, 2026 |
| Opportunity number | RFA-DK-28-115 |
| Agency | National Institutes of Health (Department of Health and Human Services) |
| Funding instrument | Cooperative agreement |
| Category | Health |
| Opportunity category | Discretionary |
| Award ceiling (max per award) | Not stated |
| Award floor (min per award) | Not stated |
| Estimated total program funding | $35,000,000 |
| Expected number of awards | 1 |
| Cost sharing or matching required | No |
| Assistance listing (CFDA/ALN) | 93.847 – Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Last updated on Grants.gov | Aug 4, 2026 |
Who can apply
- Others (see the eligibility details in the listing)
Additional eligibility information (excerpt from the listing):
This is a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Description
Excerpt from the official forecast on Grants.gov (shortened; read the full text on the official listing):
The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a multi-center longitudinal consortium conducted across 19 clinical sites to identify risk factors and biological mechanisms driving progression to youth-onset type 2 diabetes. The study is actively recruiting and following early pubertal youth at high risk for the disease with longitudinal follow-up currently underway. The current Biostatistics Research Center (BRC) serves as the consortium's central coordinating center, managing protocol implementation, data management, quality assurance, statistical design and analysis, and inter-site and consortium-wide coordination. The BRC has established the robust infrastructure and standardized processes required to support the study and preserve the integrity of the longitudinal dataset. …
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