Grant Deadlines
Forecast · not open yetCooperative agreement

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

National Institutes of Health · Department of Health and Human Services · RFA-NS-28-004

In plain English

National Institutes of Health (Department of Health and Human Services) has announced this as a forecast: an opportunity it expects to post. It is not open for applications yet. Estimated posting date: Jan 4, 2027. Estimated application due date: Mar 4, 2027.

The agency expects to make 15 awards.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusForecasted: not open yet
Estimated posting dateJan 4, 2027
Estimated application due dateMar 4, 2027
Estimated award dateDec 7, 2027
Estimated project startMar 4, 2028
Fiscal year2028
Forecast postedAug 13, 2026
Opportunity numberRFA-NS-28-004
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentCooperative agreement
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)Not stated
Award floor (min per award)Not stated
Estimated total program fundingNot stated
Expected number of awards15
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.853 – Extramural Research Programs in the Neurosciences and Neurological Disorders
Last updated on Grants.govAug 13, 2026

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Description

Excerpt from the official forecast on Grants.gov (shortened; read the full text on the official listing):

The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care. Applications are not being solicited at this time. …

Read the full forecast on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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