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Forecast · not open yetGrantUp to $375K per award

NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

National Institutes of Health · Department of Health and Human Services · RFA-DA-28-002

In plain English

National Institutes of Health (Department of Health and Human Services) has announced this as a forecast: an opportunity it expects to post. It is not open for applications yet. Estimated posting date: Feb 1, 2027. Estimated application due date: May 26, 2027.

Awards are up to $375,000 each, the agency expects to make 5 awards and estimated total program funding is $3,000,000.

Eligible applicant types include nonprofits, small businesses, for-profit companies, state governments, local governments, tribal governments & organizations, colleges & universities, school districts and public housing authorities, plus others described in the listing.

The listing says cost sharing or matching is not required.

Built only from the fields in the Grants.gov listing. Always confirm on the official listing.

Key facts

StatusForecasted: not open yet
Estimated posting dateFeb 1, 2027
Estimated application due dateMay 26, 2027
Estimated award dateApr 1, 2028
Estimated project startApr 1, 2028
Fiscal year2028
Forecast postedSep 10, 2026
Opportunity numberRFA-DA-28-002
AgencyNational Institutes of Health (Department of Health and Human Services)
Funding instrumentGrant
CategoryHealth
Opportunity categoryDiscretionary
Award ceiling (max per award)$375,000
Award floor (min per award)Not stated
Estimated total program funding$3,000,000
Expected number of awards5
Cost sharing or matching requiredNo
Assistance listing (CFDA/ALN)93.279 – Drug Use and Addiction Research Programs
Last updated on Grants.govSep 10, 2026

Who can apply

Browse similar: Nonprofits · Small businesses · For-profit companies · State governments · Local governments · Tribal governments & organizations · Colleges & universities · School districts · Public housing authorities

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Native American tribal governments (federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than federally recognized tribal governments)
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others (see the eligibility details in the listing)

Additional eligibility information (excerpt from the listing):

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Description

Excerpt from the official forecast on Grants.gov (shortened; read the full text on the official listing):

Avenir, the French word for "future," reflects NIDA's commitment to developing the next generation of leaders in addiction science. Since 2015, the Avenir Program has supported exceptionally creative early stage investigators (ESIs) in launching innovative research programs. NIDA is now expanding this program to support bold mechanistic research across a broader range of addiction science, including genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders (SUDs). This initiative is intended to catalyze high-risk, high-reward research and attract outstanding new investigators, including those from outside the addiction field. …

Read the full forecast on Grants.gov →

Before you apply: organizations applying through Grants.gov generally need an active SAM.gov registration (with a Unique Entity ID) and a Grants.gov account, and registration can take several weeks, so start early. Check the official listing for the exact requirements, deadline time and time zone. This page is a summary, not the official notice, and not legal or financial advice.

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